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This skillet dish combines the savory flavors of ground beef, pepperoni, and three types of cheese with the buttery, garlicky goodness of Cheddar Bay biscuits. The beef is browned to perfection with a hint of crust, then simmered with marinara sauce until thick and clingy. Layers of pepperoni and cheese create a gooey, melty center, while dollops of biscuit dough bake into golden, fluffy tops. Finished with garlic butter and optional Parmesan, red pepper flakes,...
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Heat a skillet over medium-high heat. Add ground beef and diced onion. Season with salt and pepper. Cook until the beef develops some crust and no visible liquid remains. Drain excess grease if needed, but leave a little for flavor.


Stir in Rao’s Homemade Marinara Sauce. Simmer for 2–3 minutes until the sauce thickens and clings to the beef. Ensure it is not soupy. Turn off the heat.
Scatter pepperoni evenly over the beef mixture. Top with Monterey Jack, cheddar, and Parmesan cheese. Optionally, sprinkle a little cheddar around the skillet edges for a crispy cheese halo.


Prepare the Cheddar Bay Biscuit Mix according to the box instructions. Spoon the dough in dollops across the top of the cheese layer. Do not smooth it flat; leave some cheese peeking through.

Bake in a preheated oven at 375–400°F for 15–18 minutes until the biscuits are golden and cooked through.
Brush the garlic butter packet over the biscuit tops. Optionally, finish with extra Parmesan, red pepper flakes, or fresh basil.
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For a crispy cheese halo, sprinkle cheddar around the skillet edges before baking.
Leave some cheese peeking through the biscuit layer for a visually appealing finish.
Drain excess grease from the beef mixture, but leave a little for added flavor.
Can I use a different marinara sauce?
Yes, you can substitute Rao’s Homemade Marinara Sauce with your preferred brand or homemade marinara.
What size skillet should I use?
A 10–12” cast iron skillet works best for this recipe.
Can I make this without the biscuit mix?
You can substitute the biscuit mix with homemade biscuit dough or another pre-made mix, but the flavor may differ.
How do I know the biscuits are cooked through?
The biscuits should be golden on top and firm to the touch. You can also insert a toothpick into the center; it should come out clean.
Can I add extra toppings?
Yes, feel free to customize with additional toppings like olives, mushrooms, or bell peppers.

