Ham and Cheese Panini
This Ham and Cheese Panini is a quick and delicious meal perfect for any time of the day. The homemade honey mustard sauce adds a delightful tangy sweetness that complements the savory ham and melted Swiss cheese. It's a simple recipe that delivers a gourmet taste in just 15 minutes.

Ingredients
Sandwich
- slices of a hearty, rustic bread (sourdough, artisan, or gluten-free sandwich bread)8
- butter, softened4tbsp
- slices ham12
- slices Swiss cheese8
Honey mustard sauce
- Dijon mustard4tbsp
- honey4tbsp
- mayonnaise4tsp
Nutrition (per serving)
Calories
271.1kcal (13.55%)
Protein
0.4g (0.8%)
Carbs
6.2g (2.25%)
Sugars
5.9g (11.8%)
Healthy Fat
8.6g
Unhealthy Fat
19.5g
% Daily Value based on a 2000 calorie diet
How to make Ham and Cheese Panini
Prepare the honey mustard sauce
- Step 1
Combine Dijon mustard, honey, and mayonnaise in a small bowl. Set aside.
Assemble the sandwich
- Step 1
Butter the outside of each piece of bread.
- Step 2
Spread the homemade honey mustard sauce on the inside of each slice of bread.
- Step 3
Place one slice of Swiss cheese on one piece of bread, then top with three ham slices and one piece of Swiss cheese. Finish layering with the second slice of bread.
Cook the panini
- Step 1
On a preheated panini press, cook the sandwich for about 5 minutes until the cheese is melted and the bread is golden brown.
- Step 2
Let the sandwich rest for 1-2 minutes before slicing and serving. Enjoy!
Nutrition (per serving)
Nutrition (per serving)
Calories
271.1kcal (13.55%)
Protein
0.4g (0.8%)
Carbs
6.2g (2.25%)
Sugars
5.9g (11.8%)
Healthy Fat
8.6g
Unhealthy Fat
19.5g
% Daily Value based on a 2000 calorie diet
Tips & Tricks
If you don’t have a panini press, you can use a skillet and cook it similar to a grilled cheese sandwich.
If you don’t have a panini press, you can use a skillet and press the sandwich down with a heavy pan.
Use freshly baked bread for the best results.
Enjoy this sandwich gluten-free. Being gluten-free, I actually use gluten-free bread in place of a rustic or sourdough slice of bread.
FAQS
Can I use a different type of cheese?
Yes, you can substitute Swiss cheese with cheddar, provolone, or any cheese that melts well.
What can I use if I don’t have a panini press?
You can use a skillet and press the sandwich down with a heavy pan or a spatula to achieve similar results.
Can I make this sandwich ahead of time?
It’s best to prepare and cook the sandwich fresh, but you can assemble it ahead of time and store it in the refrigerator until ready to cook.
Can I use a different type of mustard?
Yes, you can use yellow mustard or spicy brown mustard as an alternative to Dijon mustard.
Is there a vegetarian version of this recipe?
You can replace the ham with grilled vegetables or a vegetarian deli slice to make it vegetarian.
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Marnirni-apinthi Building, Lot Fourteen,
North Terrace, Adelaide, South Australia, 5000
Australia